Agrochemical Services

In agriculture practices, pests and diseases have a great economic significance, as per FAO estimates globally they contribute towards loses of about 20%-40% every year.

Use of Plant Protection Products is therefore very important as a failure in controlling the spread of plant pests and diseases can have disastrous consequences on agricultural production and food security.

But at the same time an improper & irrational use of such products can have serious implications on humans and animals who come in contact either directly or indirectly.

Therefore there are strict regulations for use of such products and companies manufacturing them are required to generate data to validate their efficacy and study if they are safe to use and at what levels. We at Ross, offer a variety of services as per our customers needs be it for in-house validation, development of new products or generating data as per regulatory requirements.

  1. Phys-chem analysis
  2. ATR (Analytical Test Report)
  3. Identification and Quantification of Impurities
  4. Shelf life studies
  5. Chemical Equivalence

Efficacy trials are conducted to demonstrate the effectiveness of the agrochemicals on their target pest. For instance, Efficacy of a herbicide in controlling its target weed, efficacy of an insecticide in controlling its targeted insect pests and so on for fungicides, rodenticides etc.

Persistency studies help to find the time and concentrations until when the product is persistent on the crop, different types of soil and water.

We have formed collaborations with various partners to conduct Efficacy & Persistency trials. We provide guidance based on scientific and agricultural expertise to design and conduct trials. The trials are designed with respect to the crops, land, seasons and agro-climatic zones as per the applicable regulatory guidelines

 

  1. Bio-effectiveness
  2. Phyto-toxicity
  3. Effect on parasites and predators
  4. Translocation in plants
  5. Metabolism in soil, water and plants
  6. Persistence in soil, water and plants
  7. Effect on physicochemical and biological properties of soil
  8. Effects on succeeding crops
  1. Translocation in plants
  2. Metabolism in soil, water and plants
  3. Effect on physicochemical and biological properties of soil

Residue trials are conducted to study the level of residues of agrochemicals in crop and soil post application. The residue trials are designed such that they consider the proposed mode of application, the sampling procedure and the analysis. Results of several trials carried out in different localities and under different geo-climatic conditions are required to set the Maximum Residue Levels and pre-harvest intervals.

Ross can undertake collaborative trials in the field and can also manage the transport of samples from the fields to analytical laboratories for analysis.

  1. Residues in soil
  2. Residues in plants

i. Acute Mammalian Toxicity Studies

  1. Acute Oral – Rat
  2. Acute Dermal – Rat / Rabbit
  3. Acute Inhalation
  4. Primary Skin Irritation
  5. Acute Eye Irritation
  6. Skin Sensitization*

ii. Short Term Repeated Dose Toxicity Studies

  1. Repeated Dose Range Finding Oral Toxicity Study (upto 28 Days)
  2. Repeated Dose 90 Day Oral :
    a) Toxicity Study-Rodent
    b) Toxicity Study-Non Rodent (Dog)
  3. Repeated Dose Dermal Toxicity
  4. Repeated Dose Inhalation Toxicity

iii. Neurotoxicity Studies

  1. Acute Neurotoxicity – Rodent
  2. Repeated Dose Neuro toxicity – Rodent
  3. Delayed Neurotoxicity – OP Compound – Acute Exposure
  4. Delayed Neurotoxicity – OP Compound – Repeated Administration
  5. Developmental Neurotoxicity

iv. Long Term Toxicity Studies

  1. Combined Carcinogenicity/chronic toxicity study- Rat
  2. Carcinogenicity – Rat & Mice
  3. Chronic toxicity – Rat

v. Development & Reproduction Toxicity Studies (DART)

  1. Developmental Toxicity Study – Rat & Rabbit
  2. Two Generation* Reproduction Toxicity study

vi. Genotoxicity Study

  1. Bacterial Reverse Mutation Test (AMES Test)
  2. In-Vitro Mammalian Chromosome Aberration Test
  3. In- Vitro Mammalian Cell Gene Mutation Test
  4. In-vitro Mammalian Cell Micronucleus Test
  5. In-Vivo Mammalian Bone Marrow Chromosome Aberration Test
  6. Mammalian Spermatogonial Chromosome Abberation Test
  7. In-Vivo Mammalian Erythrocyte Micronucleus Test
  8. In- Vivo Un-Scheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells
  9. Mouse Heritable Translocation Assay
  10. Rodent Dominant Lethal Test

Ecotox

Studies Guideline
Acute toxicity in earthworms OECD 207
Acute toxicity in fish OECD 203
Acute immobilization in daphnia OECD 202
Acute oral toxicity in honey bees OECD 213
Acute contact toxicity in honey bees OECD 214
Acute growth inhibition test in algae   OECD 201
Acute oral toxicity in birds   OECD 223
Daphnia magna Reproduction Test   OECD 211
  1. Container Content Compatibility
  2. Performance of container in Storage stability
  3. Transport worthiness test